Haitian women in the study were found to have elevated levels of COX-2 and PGE2. Linking HIV which causes chronic inflammation and PGE2, which is elevated during inflammation, to cancer development in several types of tumors including cervical cancer. Cyclooxgenase (COX) is found naturally in our body. COX-2 is needed in limited quantities to induce pain but when produced out of control will cause constant pain. One of the most inexpensive and effective inhibitors for COX is aspirin.
The lead researcher of the study Dr. Daniel Fitzgerald, said " these young patients, many of whom were mothers and the sole support for their families - had worked hard to have their HIV controlled with antiviral therapy, only to develop and die from cervical cancer". Researchers now want to look at exactly what population of women that may benefit from daily use of aspirin or related inhibitors.